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M94A2613.TXT
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1994-10-25
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Document 2613
DOCN M94A2613
TI HIV & hepatitis B (HBV) in women--a retrospective chart review.
DT 9412
AU Keohane DJ; Flanigan T; Feller E; Carpenter C; Miriam Hospital--Brown
Univ., Providence, RI 02906.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):264 (abstract no. PB0486). Unique
Identifier : AIDSLINE ICA10/94369962
AB OBJECTIVE: To examine the prevalence of HBV in HIV seropositive women.
METHODS: A retrospective chart review was undertaken at 3 hospital
centers. 218 HIV positive women with complete panels of HBV serologies
were included. RESULTS: In the entire cohort, the incidence of past or
present HBV infection was 143 of 218 (66%). When evaluated by risk
factor, 113 of 130 (87%) women with intravenous drug use (IDU) and 28 of
82 (34%) with unprotected heterosexual exposure were coinfected. When
evaluated by serologic pattern of HBV positivity, the following was
found. 10 (7%) women had HBsAb alone, 53 (38%) had HBcAb alone, 75 (53%)
had HBsAb/HBcAb positivity and 3 (2%) had persistence of HBsAg. All
three women with persistence of HBsAg had IDU as their risk factor.
DISCUSSION & CONCLUSION: Our data suggest that IDU represents the
highest risk behavior for coinfection of HIV and HBV in women. Our
results also show a low rate of persistent HBsAg and a high rate of
isolated HBcAb positivity in women who are coinfected as compared to
prior studies in men.
DE Cohort Studies Cross-Sectional Studies Female Hepatitis
B/*COMPLICATIONS/DIAGNOSIS/EPIDEMIOLOGY Hepatitis B Antibodies/BLOOD
Human HIV Infections/*COMPLICATIONS/DIAGNOSIS/EPIDEMIOLOGY Incidence
Retrospective Studies Rhode Island/EPIDEMIOLOGY Risk Factors MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).